陳思甫
振興醫療財團法人振興醫院
科主任
陳思甫看診時間
| 星期一 | 24 小時營業 |
| 星期二 | 24 小時營業 |
| 星期三 | 24 小時營業 |
| 星期四 | 24 小時營業 |
| 星期五 | 24 小時營業 |
| 星期六 | 24 小時營業 |
| 星期日 | 24 小時營業 |
陳思甫醫師簡介
現職
振興醫療財團法人振興醫院復健醫學部 神經復健科主任
振興醫療財團法人振興醫院教學研究部 部主任
國防醫學院生理學科兼任教授
教育部 部定教授
期刊編輯: Journal of Medical Science (2012-) Taiwan Journal of Physical Medicine and Rehabilitation (2006-)
振興醫療財團法人振興醫院教學研究部 部主任
國防醫學院生理學科兼任教授
教育部 部定教授
期刊編輯: Journal of Medical Science (2012-) Taiwan Journal of Physical Medicine and Rehabilitation (2006-)
學歷
英國劍橋大學生物醫學 博士
高雄醫學大學醫學系 醫學士
高雄醫學大學醫學系 醫學士
經歷
．高雄醫學大學醫學系
．英國劍橋大學生物醫學博士
．英國劍橋大學腦傷研究中心博士後研究員
．英國劍橋大學生物醫學博士
．英國劍橋大學腦傷研究中心博士後研究員
專長
1. 腦神經及周邊神經病變
2. 脊髓神經病變
3. 電學診斷
4. 骨關節復健
5. 疼痛復健
2. 脊髓神經病變
3. 電學診斷
4. 骨關節復健
5. 疼痛復健
其他
腦損傷與修復研究室
中樞神經損傷是導致成年人永久殘障和死亡的主要原因之一，但至今還沒有有效的治療方法。我們研究團隊 的主要目標是以臨床的角度,運用生理學及分子生物學的技術探討造成頭部外傷及腦中風續發性傷害的病理機轉，並開發可能的治療途徑。
目前，我們利用皮質撞擊腦傷、出血性腦中風、缺血性腦中風動物模式及相關之細胞模式來探討此一問題，應用基因剔除鼠、初代神經元及膠細胞培養、蛋白質分析 (Western blot 及 ELISA)、免疫染色、real-time PCR及動物行為測試等技術。我們從藥理和基因這兩方面着手，主要研究方向為：
1. 以基因剔除鼠來研究caveolin-1、epoxide hydrolase 2 (EPHX2) 、transient receptor potential vanilloid 1(TRPV1) 等不同基因對腦損傷後發炎反應、細胞凋亡和促存活訊號的影響，與相關蛋白質的調節及訊息傳遞。
2. 研究神經保護藥物對小鼠腦傷及腦中風的療效，並進行細胞分子機制探討。
3. 尋找具有鑑別性的生物標誌，協助判斷腦損傷的預後及評估藥物療效。
【近年研究計畫】
＊科技部
1. 探討抑制第一錨型瞬態電位受體運用於出血性腦中風治療之作用及其分子調控機轉 (107-2314-B-350-001-MY3) 8/1/2018- 7/31/2021
2. 探討香草精第一型瞬態電壓感受器陽離子通道於出血性腦中風所扮演之角色及其分子調控機轉 (104-2314-B-350-001-MY3) 8/1/2015- 7/31/2018
＊振興醫院院內計畫
1. 創傷性腦外傷後抑制可溶性環氧化物水解酶對認知功能障礙保護作用之探討 (CHGH109- (N)28)
2. 利用基因剔除小鼠探討C-C chemokine receptor 5 (CCR5) 在實驗性腦傷之角色及調控微小膠細胞誘發發炎反應機轉之探討 (CHGH108- 19)
3. 延遲活化Liver X receptor於實驗性腦傷神經保護功效之評估及調控微小膠細胞誘發發炎反應機轉之探討 (CHGH107- 20)
4. 延遲性給予可溶性環氧化物水解酶抑制劑於實驗性腦傷神經保護功效之評估及刺激腦源性神經滋養因子表現機轉之探討 (CHGH106-19)
5.延遲性給予可溶性環氧化物水解酶抑制劑於實驗性腦出血神經保護功效之評估及抗凋亡機轉之探討 (CHGH105- 20)
＊近五年著作 (* corresponding author)
1. H.Y. Shen, J.Y. Lin, C.C. Chen, H.F. Lee, H. Chao, F.K. Lieu, Szu-Fu Chen * (2022, Jun). Evaluation of post-stroke spasticity from the subacute to chronic stages: A clinical and neurophysiologic study of motoneuron pool excitability. Chinese Journal of Physiology. 65:109-116. (* corresponding author) (SCI, IF: 1.568; PHYSIOLOGY 75/81)
2. C.H. Lin, F.C. Wang*, T.Y. Kuo, P.W. Huang, Szu-Fu Chen, L.C. Fu (2022, Feb). Early Detection of Parkinson’s Disease by Neural Network Models. IEEE Access. 10: 19033 – 19044. (SCI, IF: 3.476; ENGINEERING, ELECTRICAL & ELECTRONIC 105/276)
3. T.H. Hung, C.P. Wu, Szu-Fu Chen* (2021, Dec). Differential changes in Akt and AMPK phosphorylation regulating mTOR activity in the placentas of pregnancies complicated by fetal growth restriction and gestational diabetes mellitus with large-for-gestational age infants. Frontiers in Medicine. 6;8:788969. eCollection 2021. (* corresponding author) (SCI, IF: 5.058; MEDICINE, GENERAL & INTERNAL 52/172)
4. F.C. Wang*, Y.C. Li, T.Y. Kuo, Szu-Fu Chen, C.H. Lin (2021, Sep). Real-Time Detection of Gait Events by Recurrent Neural Networks. IEEE Access. 9: 134849 – 134857. (SCI, IF: 3.476; ENGINEERING, ELECTRICAL & ELECTRONIC 105/276)
5. T.H. Hung*, T.T. Hsieh, S.W. Shaw, C.K. Seong, Szu-Fu Chen (2021, Jun). Risk factors and adverse maternal and perinatal outcomes for women with dichorionic twin pregnancies complicated by gestational diabetes mellitus: A retrospective cross-sectional study. Journal of Diabetes Investigation. 12(6):1083-1091. (SCI, IF: 3.690; ENDOCRINOLOGY & METABOLISM 84/146)
6. T.H. Hung, Y.C. Liu, C.H. Wu, C.C. Chen, H. Chao, F.Y. Yang*, Szu-Fu Chen* (2021, May). Antenatal low-intensity pulsed ultrasound reduces neurobehavioral deficits and brain injury following dexamethasone-induced intrauterine growth restriction. Brain Pathology. 31(6):e12968. doi: 10.1111/bpa.12968. Epub 2021 May 7. (* corresponding author) (SCI, IF: 7.611; PATHOLOGY 8/77)
7. T.H. Hung*, Y.C. Chuang, F.C. Chu, L. Huang, S.W. Shaw, T.T. Hsieh, Szu-Fu Chen (2021, May). Risk factors for abnormal postpartum glycemic states in women diagnosed with gestational diabetes by the International Association of Diabetes and Pregnancy Study Groups criteria. Journal of Diabetes Investigation. 12(5):859-868. doi: 10.1111/jdi.13400. Epub 2020 Sep 30. (SCI, IF: 3.690, ENDOCRINOLOGY & METABOLISM 84/146)
8. F.C. Wang*, Szu-Fu Chen, C.H. Lin, C.J. Shih, A.C. Lin, W. Yuan, Y.C. Li, T.Y. Kuo (2021, Mar). Detection and Classification of Stroke Gaits by Deep Neural Networks Employing Inertial Measurement Units. Sensors. 21(5):1864. (SCI, IF: 3.847; INSTRUMENTS & INSTRUMENTATION 19/64)
9. P.H. Ku, Szu-Fu Chen, Y.R. Yang, T.C. Lai*, R.Y. Wang* (2020, Jan). The effects of Ai Chi for balance in individuals with chronic stroke: a randomized controlled trial. Scientific Reports. 10(1):1201. (SCI, IF: 4.996; MULTIDISCIPLINARY SCIENCES 19/73)
10. T.H. Hung*, S.Y. Huang, Szu-Fu Chen, C.P. Wu, T.T. Hsieh (2020, Jan). Decreased placental apoptosis and autophagy in pregnancies complicated by gestational diabetes with large-for-gestational age fetuses. Placenta. 90:27-36. (SCI, IF: 3.287; DEVELOPMENTAL BIOLOGY 14/39)
11. T.H. Hung*, Szu-Fu Chen, C.H. Wu, C.P. Wu (2019, Dec). Increased soluble epoxide hydrolase in human gestational tissues from pregnancies complicated by acute chorioamnionitis. Mediators of Inflammation. Volume 2019, Article ID 8687120. (SCI, IF: 4.529; IMMUNOLOGY 85/161)
12. T.H. Hung*, Szu-Fu Chen, T.T. Hsieh. (2019, Dec). Soluble epoxide hydrolase in the human placenta through gestation. Taiwanese Journal of Obstetrics & Gynecology. 58(6):840-845. (SCI, IF: 1.944; OBSTETRICS & GYNECOLOGY 72/85)
13. C.H. Wu, C.C. Chen, T.H. Hung, Y.C. Chang, M. Chao, S.S. Shyue*, Szu-Fu Chen* (2019, Jul). Activation of TrkB/Akt signaling by a TrkB receptor agonist improves long-term histological and functional outcomes in experimental intracerebral hemorrhage. Journal of Biomedical Science. 26(1):53. (* corresponding author) (SCI, IF: 12.771; MEDICINE, RESEARCH & EXPERIMENTAL 11/139)
14. J.Y. Lin, M.H. Teng, F.K. Lieu, Szu-Fu Chen* (2018, Dec). Idiopathic thoracic intradural spinal arachnoid cyst associated with syringomyelia-case report and literature review. Taiwan Journal of Physical Medicine and Rehabilitation, 46(2):107-112. (* corresponding author) (TSCI)
15. Y.T. Cheng, Szu-Fu Chen, T.T. Hsieh, T.H. Hung* (2018, Oct). A comparison of the efficacy of carbetocin and oxytocin on hemorrhage-related changes in women with cesarean deliveries for different indications. Taiwanese Journal of Obstetrics and Gynecology. 57(5):667-682. (SCI, IF: 1.944; OBSTETRICS & GYNECOLOGY 72/85)
16. Szu-Fu Chen, W.S. Su, C.H. Wu, T.H. Lang, F.Y. Yang*. (2018, Aug). Transcranial ultrasound stimulation improves long-term functional outcomes and protects against brain damage in traumatic brain injury. 16. Molecular Neurobiology. 55(8):7079-7089. (SCI, IF: 5.687; NEUROSCIENCES 68/274)
17. T.H. Hung*, T.T. Hsieh, Szu-Fu Chen (2018, Apr). Risk of abnormal fetal growth in women with early- and late-onset preeclampsia. Pregnancy Hypertension-An International Journal of Women’s Cardiovascular Health. 12:201-206. (SCI, IF: 2.494; OBSTETRICS & GYNECOLOGY 57/85)
18. T.H. Hung*, T.T. Hsieh, C.P. Wu, M.J. Li, Y.L. Yeh, Szu-Fu Chen (2017, Dec). Mammalian target of rapamycin signaling is a mechanistic link between increased endoplasmic reticulum stress and autophagy in the placentas of pregnancies complicated by growth restriction. Placenta. 60:9-20. (SCI, IF: 3.287; DEVELOPMENTAL BIOLOGY 14/39)
19. C.H. Wu, S.S. Shyue, T.H. Hung, S. Wen, C.C. Lin, C.C. Chang, Szu-Fu Chen* (2017 Nov). Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage. Journal of Neuroinflammation. 25;14(1):230. (* corresponding author) (SCI, IF: 9.594; NEUROSCIENCES 24/274)
20. W.S. Su, C.H. Wu, Szu-Fu Chen*, F.Y. Yang* (2017, Nov). Transcranial ultrasound stimulation promotes brain-derived neurotrophic factor and reduces apoptosis in a mouse model of traumatic brain injury. Brain Stimulation. 10(6): 1032-1041. (* corresponding author) (SCI, IF: 9.184; CLINICAL NEUROLOGY 17/212)
21. W.S. Su, C.H. Wu, Szu-Fu Chen*, F.Y. Yang (2017, Nov). Low-intensity pulsed ultrasound improves behavioral and histological outcomes after experimental traumatic brain injury. Scientific Reports. 7(1):15524. (* corresponding author) (SCI, IF: 4.996; MULTIDISCIPLINARY SCIENCES 19/73)
22. T.H. Hung, S.S. Shyue, C.H. Wu, C.C. Chen, C.C. Lin, C.C. Chang, Szu-Fu Chen* (2017, Sep). Deletion or inhibition of soluble epoxide hydrolase protects against brain damage and reduces microglia-mediated neuroinflammation in traumatic brain injury. Oncotarget. 8(61):103236-103260. (* corresponding author) (SCI, IF: 5.168; ONCOLOGY 44/217, JCR 2016)
23. T.H. Hung*, Szu-Fu Chen, C.P. Wu, M.J. Li, Y.L. Yeh, T.T. Hsieh* (2017, Sep). Micronized progesterone pretreatment affects the inflammatory response of human gestational tissues and the cervix to lipopolysaccharide stimulation. Placenta. 57:1-8. (SCI, IF: 3.287; DEVELOPMENTAL BIOLOGY 14/39)
24. C.C. Huang, C.H. Wu, Y.Y. Huang, K.Y. Tzen, Szu-Fu Chen, M.L. Tsai, H.M. Wu* (2017, Apr). Performing repeated quantitative small animal PET studies with arterial input functions is routinely- feasible in rats. Journal of Nuclear Medicine. 58(4):611-616. (SCI, IF: 11.082; RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 4/136)
＊專書
1. 陳嘉玲、陳思甫：Chp. 32頭部外傷之復健. 復健及物理醫學 (編輯: 連倚南等)，ISBN 9789863682059 合記出版社, 2013, pp.659-712.
2. 陳嘉玲、陳思甫：Chp. 18 創傷性腦損傷後之復健. 復健醫學 (編輯: 連倚南等)，ISBN 9789861269085合記出版社, 2017, pp.243-260.
中樞神經損傷是導致成年人永久殘障和死亡的主要原因之一，但至今還沒有有效的治療方法。我們研究團隊 的主要目標是以臨床的角度,運用生理學及分子生物學的技術探討造成頭部外傷及腦中風續發性傷害的病理機轉，並開發可能的治療途徑。
目前，我們利用皮質撞擊腦傷、出血性腦中風、缺血性腦中風動物模式及相關之細胞模式來探討此一問題，應用基因剔除鼠、初代神經元及膠細胞培養、蛋白質分析 (Western blot 及 ELISA)、免疫染色、real-time PCR及動物行為測試等技術。我們從藥理和基因這兩方面着手，主要研究方向為：
1. 以基因剔除鼠來研究caveolin-1、epoxide hydrolase 2 (EPHX2) 、transient receptor potential vanilloid 1(TRPV1) 等不同基因對腦損傷後發炎反應、細胞凋亡和促存活訊號的影響，與相關蛋白質的調節及訊息傳遞。
2. 研究神經保護藥物對小鼠腦傷及腦中風的療效，並進行細胞分子機制探討。
3. 尋找具有鑑別性的生物標誌，協助判斷腦損傷的預後及評估藥物療效。
【近年研究計畫】
＊科技部
1. 探討抑制第一錨型瞬態電位受體運用於出血性腦中風治療之作用及其分子調控機轉 (107-2314-B-350-001-MY3) 8/1/2018- 7/31/2021
2. 探討香草精第一型瞬態電壓感受器陽離子通道於出血性腦中風所扮演之角色及其分子調控機轉 (104-2314-B-350-001-MY3) 8/1/2015- 7/31/2018
＊振興醫院院內計畫
1. 創傷性腦外傷後抑制可溶性環氧化物水解酶對認知功能障礙保護作用之探討 (CHGH109- (N)28)
2. 利用基因剔除小鼠探討C-C chemokine receptor 5 (CCR5) 在實驗性腦傷之角色及調控微小膠細胞誘發發炎反應機轉之探討 (CHGH108- 19)
3. 延遲活化Liver X receptor於實驗性腦傷神經保護功效之評估及調控微小膠細胞誘發發炎反應機轉之探討 (CHGH107- 20)
4. 延遲性給予可溶性環氧化物水解酶抑制劑於實驗性腦傷神經保護功效之評估及刺激腦源性神經滋養因子表現機轉之探討 (CHGH106-19)
5.延遲性給予可溶性環氧化物水解酶抑制劑於實驗性腦出血神經保護功效之評估及抗凋亡機轉之探討 (CHGH105- 20)
＊近五年著作 (* corresponding author)
1. H.Y. Shen, J.Y. Lin, C.C. Chen, H.F. Lee, H. Chao, F.K. Lieu, Szu-Fu Chen * (2022, Jun). Evaluation of post-stroke spasticity from the subacute to chronic stages: A clinical and neurophysiologic study of motoneuron pool excitability. Chinese Journal of Physiology. 65:109-116. (* corresponding author) (SCI, IF: 1.568; PHYSIOLOGY 75/81)
2. C.H. Lin, F.C. Wang*, T.Y. Kuo, P.W. Huang, Szu-Fu Chen, L.C. Fu (2022, Feb). Early Detection of Parkinson’s Disease by Neural Network Models. IEEE Access. 10: 19033 – 19044. (SCI, IF: 3.476; ENGINEERING, ELECTRICAL & ELECTRONIC 105/276)
3. T.H. Hung, C.P. Wu, Szu-Fu Chen* (2021, Dec). Differential changes in Akt and AMPK phosphorylation regulating mTOR activity in the placentas of pregnancies complicated by fetal growth restriction and gestational diabetes mellitus with large-for-gestational age infants. Frontiers in Medicine. 6;8:788969. eCollection 2021. (* corresponding author) (SCI, IF: 5.058; MEDICINE, GENERAL & INTERNAL 52/172)
4. F.C. Wang*, Y.C. Li, T.Y. Kuo, Szu-Fu Chen, C.H. Lin (2021, Sep). Real-Time Detection of Gait Events by Recurrent Neural Networks. IEEE Access. 9: 134849 – 134857. (SCI, IF: 3.476; ENGINEERING, ELECTRICAL & ELECTRONIC 105/276)
5. T.H. Hung*, T.T. Hsieh, S.W. Shaw, C.K. Seong, Szu-Fu Chen (2021, Jun). Risk factors and adverse maternal and perinatal outcomes for women with dichorionic twin pregnancies complicated by gestational diabetes mellitus: A retrospective cross-sectional study. Journal of Diabetes Investigation. 12(6):1083-1091. (SCI, IF: 3.690; ENDOCRINOLOGY & METABOLISM 84/146)
6. T.H. Hung, Y.C. Liu, C.H. Wu, C.C. Chen, H. Chao, F.Y. Yang*, Szu-Fu Chen* (2021, May). Antenatal low-intensity pulsed ultrasound reduces neurobehavioral deficits and brain injury following dexamethasone-induced intrauterine growth restriction. Brain Pathology. 31(6):e12968. doi: 10.1111/bpa.12968. Epub 2021 May 7. (* corresponding author) (SCI, IF: 7.611; PATHOLOGY 8/77)
7. T.H. Hung*, Y.C. Chuang, F.C. Chu, L. Huang, S.W. Shaw, T.T. Hsieh, Szu-Fu Chen (2021, May). Risk factors for abnormal postpartum glycemic states in women diagnosed with gestational diabetes by the International Association of Diabetes and Pregnancy Study Groups criteria. Journal of Diabetes Investigation. 12(5):859-868. doi: 10.1111/jdi.13400. Epub 2020 Sep 30. (SCI, IF: 3.690, ENDOCRINOLOGY & METABOLISM 84/146)
8. F.C. Wang*, Szu-Fu Chen, C.H. Lin, C.J. Shih, A.C. Lin, W. Yuan, Y.C. Li, T.Y. Kuo (2021, Mar). Detection and Classification of Stroke Gaits by Deep Neural Networks Employing Inertial Measurement Units. Sensors. 21(5):1864. (SCI, IF: 3.847; INSTRUMENTS & INSTRUMENTATION 19/64)
9. P.H. Ku, Szu-Fu Chen, Y.R. Yang, T.C. Lai*, R.Y. Wang* (2020, Jan). The effects of Ai Chi for balance in individuals with chronic stroke: a randomized controlled trial. Scientific Reports. 10(1):1201. (SCI, IF: 4.996; MULTIDISCIPLINARY SCIENCES 19/73)
10. T.H. Hung*, S.Y. Huang, Szu-Fu Chen, C.P. Wu, T.T. Hsieh (2020, Jan). Decreased placental apoptosis and autophagy in pregnancies complicated by gestational diabetes with large-for-gestational age fetuses. Placenta. 90:27-36. (SCI, IF: 3.287; DEVELOPMENTAL BIOLOGY 14/39)
11. T.H. Hung*, Szu-Fu Chen, C.H. Wu, C.P. Wu (2019, Dec). Increased soluble epoxide hydrolase in human gestational tissues from pregnancies complicated by acute chorioamnionitis. Mediators of Inflammation. Volume 2019, Article ID 8687120. (SCI, IF: 4.529; IMMUNOLOGY 85/161)
12. T.H. Hung*, Szu-Fu Chen, T.T. Hsieh. (2019, Dec). Soluble epoxide hydrolase in the human placenta through gestation. Taiwanese Journal of Obstetrics & Gynecology. 58(6):840-845. (SCI, IF: 1.944; OBSTETRICS & GYNECOLOGY 72/85)
13. C.H. Wu, C.C. Chen, T.H. Hung, Y.C. Chang, M. Chao, S.S. Shyue*, Szu-Fu Chen* (2019, Jul). Activation of TrkB/Akt signaling by a TrkB receptor agonist improves long-term histological and functional outcomes in experimental intracerebral hemorrhage. Journal of Biomedical Science. 26(1):53. (* corresponding author) (SCI, IF: 12.771; MEDICINE, RESEARCH & EXPERIMENTAL 11/139)
14. J.Y. Lin, M.H. Teng, F.K. Lieu, Szu-Fu Chen* (2018, Dec). Idiopathic thoracic intradural spinal arachnoid cyst associated with syringomyelia-case report and literature review. Taiwan Journal of Physical Medicine and Rehabilitation, 46(2):107-112. (* corresponding author) (TSCI)
15. Y.T. Cheng, Szu-Fu Chen, T.T. Hsieh, T.H. Hung* (2018, Oct). A comparison of the efficacy of carbetocin and oxytocin on hemorrhage-related changes in women with cesarean deliveries for different indications. Taiwanese Journal of Obstetrics and Gynecology. 57(5):667-682. (SCI, IF: 1.944; OBSTETRICS & GYNECOLOGY 72/85)
16. Szu-Fu Chen, W.S. Su, C.H. Wu, T.H. Lang, F.Y. Yang*. (2018, Aug). Transcranial ultrasound stimulation improves long-term functional outcomes and protects against brain damage in traumatic brain injury. 16. Molecular Neurobiology. 55(8):7079-7089. (SCI, IF: 5.687; NEUROSCIENCES 68/274)
17. T.H. Hung*, T.T. Hsieh, Szu-Fu Chen (2018, Apr). Risk of abnormal fetal growth in women with early- and late-onset preeclampsia. Pregnancy Hypertension-An International Journal of Women’s Cardiovascular Health. 12:201-206. (SCI, IF: 2.494; OBSTETRICS & GYNECOLOGY 57/85)
18. T.H. Hung*, T.T. Hsieh, C.P. Wu, M.J. Li, Y.L. Yeh, Szu-Fu Chen (2017, Dec). Mammalian target of rapamycin signaling is a mechanistic link between increased endoplasmic reticulum stress and autophagy in the placentas of pregnancies complicated by growth restriction. Placenta. 60:9-20. (SCI, IF: 3.287; DEVELOPMENTAL BIOLOGY 14/39)
19. C.H. Wu, S.S. Shyue, T.H. Hung, S. Wen, C.C. Lin, C.C. Chang, Szu-Fu Chen* (2017 Nov). Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage. Journal of Neuroinflammation. 25;14(1):230. (* corresponding author) (SCI, IF: 9.594; NEUROSCIENCES 24/274)
20. W.S. Su, C.H. Wu, Szu-Fu Chen*, F.Y. Yang* (2017, Nov). Transcranial ultrasound stimulation promotes brain-derived neurotrophic factor and reduces apoptosis in a mouse model of traumatic brain injury. Brain Stimulation. 10(6): 1032-1041. (* corresponding author) (SCI, IF: 9.184; CLINICAL NEUROLOGY 17/212)
21. W.S. Su, C.H. Wu, Szu-Fu Chen*, F.Y. Yang (2017, Nov). Low-intensity pulsed ultrasound improves behavioral and histological outcomes after experimental traumatic brain injury. Scientific Reports. 7(1):15524. (* corresponding author) (SCI, IF: 4.996; MULTIDISCIPLINARY SCIENCES 19/73)
22. T.H. Hung, S.S. Shyue, C.H. Wu, C.C. Chen, C.C. Lin, C.C. Chang, Szu-Fu Chen* (2017, Sep). Deletion or inhibition of soluble epoxide hydrolase protects against brain damage and reduces microglia-mediated neuroinflammation in traumatic brain injury. Oncotarget. 8(61):103236-103260. (* corresponding author) (SCI, IF: 5.168; ONCOLOGY 44/217, JCR 2016)
23. T.H. Hung*, Szu-Fu Chen, C.P. Wu, M.J. Li, Y.L. Yeh, T.T. Hsieh* (2017, Sep). Micronized progesterone pretreatment affects the inflammatory response of human gestational tissues and the cervix to lipopolysaccharide stimulation. Placenta. 57:1-8. (SCI, IF: 3.287; DEVELOPMENTAL BIOLOGY 14/39)
24. C.C. Huang, C.H. Wu, Y.Y. Huang, K.Y. Tzen, Szu-Fu Chen, M.L. Tsai, H.M. Wu* (2017, Apr). Performing repeated quantitative small animal PET studies with arterial input functions is routinely- feasible in rats. Journal of Nuclear Medicine. 58(4):611-616. (SCI, IF: 11.082; RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 4/136)
＊專書
1. 陳嘉玲、陳思甫：Chp. 32頭部外傷之復健. 復健及物理醫學 (編輯: 連倚南等)，ISBN 9789863682059 合記出版社, 2013, pp.659-712.
2. 陳嘉玲、陳思甫：Chp. 18 創傷性腦損傷後之復健. 復健醫學 (編輯: 連倚南等)，ISBN 9789861269085合記出版社, 2017, pp.243-260.
