姚宗珍醫師詳細介紹

探討組織以及細胞受力之反應速率：
施予牙齒的力量經由刺激牙周組織的活性，細胞與組織因受力與微血管通透與氧氣供應調節而產生骨吸收及骨沉積，進而在齒槽骨內移動，其機械力刺激大小和頻率的特性，以及牙齒位移速度的影響因子，在牙齒矯正學之中是一個尚處於萌芽的研究課題。是否有可早期偵測矯正病人牙齒移動速度的標記，或可指認出引發多個下游的基因表現的關鍵因素？找到關鍵因子後，將可瞭解骨質受機械力的代謝機制，從而找到調節這些變化的適當施力的大小和頻率以及尋找同樣受壓力調控的基因群組，未來臨床可能開發早期預測牙齒移動速率或開發加速矯正牙齒冗長的治療過程之策略，以降低昂貴的治療成本，和減少病患在治療中，因口腔衛生不易維護導致蛀牙或牙周病的罹患率。

顳顎關節骨關節炎引發下顎骨髁突骨吸收之基因關聯分析

下顎骨髁頭的退化性吸收往往引起開咬的問題，使用矯正迷你植體之矯正治療病例追蹤研究得知，結果多屬穩定，咬合均可以獲得改善，但偶見持續的髁頭的退化性吸收，會再度使咬合功能退減，收集病人基因用以基因關聯研究，將可以對下顎骨髁突骨吸收機制進一步確認，未來在治療時對的顳顎關節骨關節炎預測與治療方針會有更多的突破。

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