Five-item Sino-Nasal Outcome Test in Evaluation of Disease Burden in Chronic Rhinosinusitis With Nasal Polyps. 2025 Dec 3:19458924251399711. doi: 10.1177/19458924251399711. Online ahead of print. Pei-Wen Wu, Chi-Che Huang, Po-Hung Chang, Ta-Jen Lee, Chien-Chia Huang*.
Postoperative Sleep Outcomes in Empty Nose Syndrome: Associations With Psychiatric Symptomatology. Int Forum Allergy Rhinol. 2025 Nov;15(11):1209-1216. Hsiang-An Hsueh, Ta-Jen Lee, Li-Pang Chuang, Chi-Che Huang, Yi-Wei Chen, Po-Hung Chang, Chia-Chen Wu, Ya-Cheng Tang, Chia-Hsiang Fu*.
Concerns on Sleep Assessment Complexity and Nasal Resistance Effects in Empty Nose Syndrome. Int Forum Allergy Rhinol. 2025 Aug;15(8):881-883. Hsiang-An Hsueh, Ta-Jen Lee, Li-Pang Chuang, Chi-Che Huang, Yi-Wei Chen, Po-Hung Chang, Chia-Chen Wu, Ya-Cheng Tang, Chia-Hsiang Fu*.
Predictive Value of Computed Tomographic Ethmoid-to-Maxillary Ratio in Patients with Chronic Rhinosinusitis and Nasal Polyp. J Asthma Allergy. 2025 Aug 12:18:1167-1177. Pei-Wen Wu, Zih-Hao Wei, Chi-Che Huang, Po-Hung Chang, Ta-Jen Lee, Chien-Chia Huang*.
Postoperative Sleep Outcomes in Empty Nose Syndrome: Associations With Psychiatric Symptomatology. Int Forum Allergy Rhinol. 2025 May 30:e3615. Hsiang-An Hsueh, Ta-Jen Lee, Li-Pang Chuang, Chi-Che Huang, Yi-Wei Chen, Po-Hung Chang, Chia-Chen Wu, Ya-Cheng Tang, Chia-Hsiang Fu*.
(Hsiang-An Hsueh and Ta-Jen Lee contributed equally to this work.)
Association Between Autonomic Dysfunction and Empty Nose Syndrome. Int Forum Allergy Rhinol. 2025 May 30:e23618. Cheng-Yu Li, Ta-Jen Lee, Yi-Wei Chen, Po-Hung Chang, Ya-Cheng Tang, Yu-Chieh Chen, Shu-Yen Wan, Chia-Hsiang Fu*.
(Cheng-Yu Li and Ta-Jen Lee contributed equally to this work.)
Impact of Comorbid Asthma on Life Quality of Patients with Chronic Rhinosinusitis and Nasal Polyps. J Asthma Allergy. 2025 Apr 17:18:567-578. Pei-Wen Wu# 1, Po-Hung Chang# 1, Chi-Che Huang, Ta-Jen Lee, Yu-Hsi Fan, Chien-Chia Huang*.
(# 1These authors contributed equally to this work.)
Postoperative Adjuvant Dupilumab Improved Immediate Recovery in Patients With Advanced Type 2 Chronic Rhinosinusitis: An Exploratory Pilot Study. Int Forum Allergy Rhinol. 2025 Apr;15(4):455-459. Yan-Ting Ho, Hsiang-Sheng Wang, Ta-Jen Lee, Po-Hung Chang, Chia-Chen Wu, Chia-Hsiang Fu*.
Post-irradiation Sinus Mucosa Disease in Nasopharyngeal Carcinoma Patients Treated With Proton Therapy. Laryngoscope. 2024 Dec 23. doi: 10.1002/lary.31974. Online ahead of print. Pei-Wen Wu, Chi-Che Huang, Po-Hung Chang, Ta-Jen Lee, Chien-Yu Lin, Joseph Tung-Chieh Chang, Chien-Chia Huang*.
Biphenotypic sinonasal sarcoma in a toddler: a case report and literature review. Eur Arch Otorhinolaryngol. 2024 Dec 7. doi: 10.1007/s00405-024-09121-x. Online ahead of print. Tzu-Kung Wang, Ta-Jen Lee, Po-Hung Chang, Chia-Chen Wu, Chia-Hsiang Fu*.
Blood Eosinophil Count is the Dominant Clinical Marker for type 2 Inflammatory Severity in CRSwNP. Laryngoscope. 2024 Nov 27. doi: 10.1002/lary.31899. Online ahead of print. Pei-Wen Wu, Chi-Che Huang, Po-Hung Chang, Ta-Jen Lee, Yu-Hsi Fan, Chien-Chia Huang*.
Comparison on functional and esthetic outcomes between single and combined surgery to crooked nose deformities. J Plast Reconstr Aesthet Surg. 2024 Nov 25:101:1-6. doi: 10.1016/j.bjps.2024.11.026. Online ahead of print. Soo Ha Kwon, Ta-Jen Lee, Yen-Chang Hsiao, Chien-Chia Huang, Chia-Hsiang Fu, Cheng-I Yen*.
Outcome Analysis of Solitary Extramedullary Plasmacytoma in the Head and Neck: A Clinical Perspective. Head Neck. 2024 Nov 18. doi: 10.1002/hed.27998. Online ahead of print. Po-Wen Chuang, Wen-Yu Chuang, Ta-Jen Lee, Po-Hung Chang, Yi-Wei Chen, Chia-Hsiang Fu*.
Serum Aspergillus fumigatus-Specific IgG as a Complementary Biomarker in Differentiating Endotypes of Chronic Rhinosinusitis: A Study on Its Role and Diagnostic Efficacy in Type 2 Inflammation. Am J Rhinol Allergy. 2024 Sep;38(5):316-323. Pei-Tzu Hung, Hsiang-Sheng Wang, Ta-Jen Lee, Chi-Che Huang, Po-Hung Chang, Yi-Wei Chen, Chia-Hsiang Fu*.
The benefit of dupilumab as a postoperative short-term adjuvant therapy for chronic rhinosinusitis with nasal polyps: A preliminary study. Laryngoscope Investig Otolaryngol. 2024 Jul 3;9(4):e1296. Pei Wen Wu, Chi Che Huang, Po Hung Chang, Ta Jen Lee, Chien Chia Huang*.
Morphology, Not Only Volume: A Study on Empty Nose Syndrome and Inferior Turbinates. Laryngoscope. 2024 Jul;134(7):3060-3066. Chia-Hsiang Fu, Chien-Cheng Chen, Chi-Che Huang, Po-Hung Chang, Yi-Wei Chen, Ya-Cheng Tang, Ta-Jen Lee*.
Computed Tomographic Evaluations in Patients with Empty Nose Syndrome. Laryngoscope. 2024 May;134(5):2105-2110. Chien-Chia Huang, Ping Hsueh Sun, Pei-Wen Wu, Chi-Che Huang, Po-Hung Chang, Chia-Hsiang Fu, Ta-Jen Lee*.
Risk Factors for Isolated Sphenoid Sinusitis after Endoscopic Endonasal Transsphenoidal Pituitary Surgery. Diagnostics (Basel). 2024 Apr 2;14(7):758. Yun-Chen Chang#, Yu-Ning Tsao#, Chi-Cheng Chuang, Cheng-Yu Li, Ta-Jen Lee, Chia-Hsiang Fu, Kuo-Chen Wei, Chi-Che Huang*.(# These authors contributed equally to this work.)
Functional Exercise Capacity and Perceived Exertion in Patients with Empty Nose Syndrome. Diagnostics (Basel). 2024 Apr 24;14(9):885. Wei-Te Hung#, Ta-Jen Lee#, Pei-Wen Wu, Chi-Che Huang, Po-Hung Chang, Chien-Chia Huang*.
(# These authors contributed equally to this work.)
Identifying the Risk Factors for Orbital Complications in Isolated Sphenoid Rhinosinusitis. Medicina (Kaunas). 2024 Jan 10;60(1):128. Shiaw-Yu Chang#, Chi-Che Huang#, Yu-Hsi Fan, Pei-Wen Wu, Ta-Jen Lee, Po-Hung Chang, Chien-Chia Huang*.(#These authors contributed equally to this work.)
Clinical Characteristics of Eosinophilic Chronic Rhinosinusitis with Nasal Polyps in Adolescents. J Asthma Allergy. 2023 Oct 30:16:1197-1206. Chien-Chia Huang, Po-Hung Chang*, Yen-Lin Huang, Ta-Jen Lee, Chi-Che Huang, Pei-Wen Wu*.
(*These authors contributed equally to this work.)
Predicting the Probability of the Incidence of Maxillary Sinus Fungus Ball in Patients Using Nomogram Models. Diagnostics (Basel). 2023 Oct 9;13(19):3156. Yu-Hsi Fan, Kai-Yi Shih, Pei-Wen Wu, Yen-Lin Huang, Ta-Jen Lee, Chi-Che Huang,Po-Hung Chang, Chien-Chia Huang*.
Impact of sleep dysfunction on psychological burden in patients with empty nose syndrome. Int Forum Allergy Rhinol. 2022 Nov;12(11):1447-1450. Chien-Chia Huang, Pei-Wen Wu*, Yun-Shien Lee, Chi-Che Huang, Po-Hung Chang, Chia-Hsiang Fu, Ta-Jen Lee*.
Predictors of Surgical Intervention for Pediatric Acute Rhinosinusitis with Periorbital Infection. J Clin Med. 2022 Jul 1;11(13):3831. Pei-Wen Wu, Yen-Ling Lin, Yun-Shien Lee, Cheng-Hsun Chiu, Ta-Jen Lee, Chien-Chia Huang*.
Comparison of SNOT-25 and ENS6Q in evaluating patients with empty nose syndrome. Laryngoscope Investig Otolaryngol. 2022 Feb 28;7(2):342-348. Chien-Chia Huang; Pei-Wen Wu; Cheng-Chi Lee; Chi-Che Huang; Chia-Hsiang Fu; Po-Hung Chang*; Ta-Jen Lee *.
Suicidal thoughts in patients with empty nose syndrome. Laryngoscope Investig Otolaryngol. 2022 Jan 19;7(1):22-28. Chien-Chia Huang; Pei-Wen Wu; Cheng-Chi Lee; Po-Hung Chang; Chi-Che Huang*; Ta-Jen Lee*.
Serum High-Sensitivity C-Reactive Protein Is Associated with Postoperative Psychiatric Status in Patients with Empty Nose Syndrome. Diagnostics (Basel). 2021 Dec 18;11(12):2388. Chia-Hsiang Fu; Hung-Chin Chen; Chi-Che Huang; Po-Hung Chang; Ta-Jen Lee*.
Distinct Histopathology Characteristics in Empty Nose Syndrome. Laryngoscope. 2021 Jan;131(1):E14-E18. Ching-Lung Wu; Chia-Hsiang Fu; Ta-Jen Lee*.
The Role of Surgery in Treating Nasal Obstruction to Control Asthma. J Asthma Allergy. 2020 Nov 16;13:625-632. Pei-Wen Wu; Ta-Jen Lee; Chun-Hua Wang; Chi-Che Huang; Po-Hung Chang; Chia-Hsiang Fu;Chien-Chia Huang*.
Removal of Displaced Dental Implants in the Maxillary Sinus Using Endoscopic Approaches. Ear Nose Throat J. 2020 Jun 11; 145561320931304. doi: 10.1177/0145561320931304. Online ahead of print. Po-Hung Chang; Yi-Wei Chen; Chi-Che Huang; Chia-Hsiang Fu; Chien-Chia Huang; Ta-Jen Lee*.
Endoscopic sinus surgery for pediatric patients: Prognostic factors related to revision surgery. Laryngoscope. 2020 Apr;130(4):1051-1055. Pei-Wen Wu; Chien-Chia Huang; Shih-Wei Yang; Yen-Lin Huang; Chi-Che Huang; Po-Hung Chang; Yun-Shien Lee; Ta-Jen Lee*.
Differential IL-17A Response to S. Pneumoniae in Adenoid Tissue of Children With Sleep Disordered Breathing and Otitis Media With Effusion. Sci Rep. 2019 Dec 27; 9(1):19839. Chien-Chia Huang; Pei-Wen Wu; Ta-Jen Lee; Chyi-Liang Chen; Chun-Hua Wang; Chi-Neu Tsai; Cheng-Hsun Chiu*.
What drives depression in empty nose syndrome? A Sinonasal Outcome Test-25 subdomain analysis. Rhinology. Rhinology. 2019 Dec 1;57(6):469-476. Chien-Chia Huang; Pei-Wen Wu; Chia-Hsiang Fu; Chi-Che Huang; Po-Hung Chang; Ching-Lung Wu; Ta-Jen Lee*.
Increased nasal matrix metalloproteinase-1 and -9 expression in smokers with chronic rhinosinusitis and asthma. Sci Rep. 2019 Oct 25; 9(1): 15357. Chien-Chia Huang; Chun-Hua Wang; Pei-Wen Wu; Jung-Ru He; Chi-Che Huang; Po-Hung Chang; Chia-Hsiang Fu; Ta-Jen Lee*.
Nasal nitric oxide in relation to psychiatric status of patients with empty nose syndrome. Nitric Oxide. 2019 Aug 10; 92:55-59. Chia-Hsiang Fu; Ching-Lung Wu; Chi-Che Huang; Po-Hung Chang; Yi-Wei Chen; Ta-Jen Lee*.
Impact of cigarette smoke and IL-17A activation on asthmatic patients with chronic rhinosinusitis. Rhinology. 2019 Feb 1; 57(1):57-66. Chien-Chia Huang#; Ta-Jen Lee#; Chi-Che Huang; Po-Hung Chang; Chia-Hsiang Fu; Pei-Wen Wu; Chun-Hua Wang*.# these authors contributed equally to this work.# these authors contributed equally to this work.
A paradigm for evaluation and management of the maxillary sinus before dental implantation. Laryngoscope. 2018 Jun; 128(6):1261-1267. Yi-Wei Chen; Fu-Yin g Lee Po-Hung Chang; Chi-Che Huang; Chia-Hsiang Fu; Chien-Chia Huang; Ta-Jen Lee*.
Surgical outcome for empty nose syndrome: Impact of implantation site. Laryngoscope. 2018 Mar; 128(3):554-559. Ta-Jen Lee*; Chia-Hsiang Fu ; Ching-Lung Wu; Yi-Chan Lee; Chi-Che Huang; Po-Hung Chang; Yi-Wei Chen; Hsiao-Jung Tseng.
Surgical outcome for empty nose syndrome: Impact of implantation site. Laryngoscope. 2018 Mar;128(3):554-559. Ta-Jen Lee*; Chia-Hsiang Fu ; Ching-Lung Wu; Yi-Chan Lee; Chi-Che Huang;Po-Hung Chang; Yi-Wei Chen; Hsiao-Jung Tseng.
Impact of influenza vaccine on childhood otitis media in Taiwan: A population-based study. PLoS One. 2018 Jan 5; 13(1):e0190507. Pei-Wen Wu; Chien-Chia Huang; Wei-Chieh Chao; Chi-Chin Sun; Cheng-Hsun Chiu* ; Ta-Jen Lee*.
An unusual presentation of multiple myeloma with unilateral sudden vision loss: A case report. Medicine (Baltimore). 2017 Jun; 96(25):e7277. Pei-Wen Wu; Ta-Jen Lee; Jim-Ray Chen; Chien-Chia Huang*.
Impact of nasal symptoms on the evaluation of asthma control. Medicine (Baltimore). 2017 Feb; 96(8):e6147. Chien-Chia Huang; Po-Hung Chang; Pei-Wen Wu; Chun-Hua Wang; Chia-Hsiang Fu; Chi-Che Huang; Hsiao-Jung Tseng; Ta-Jen Lee*.
Impact of chronic rhinosinusitis on severe asthma patients. PLoS One. 2017 Feb 15; 12(2):e0171047. Ta-Jen Lee; Chia-Hsiang Fu; Chun-Hua Wang; Chi-Che Huang; Chien-Chia Huang; Po-Hung Chang; Yi-Wei Chen; Chia-Chen Wu; Ching-Lung Wu; Han-Pin Kuo*.
Association between cigarette smoking and interleukin-17A expression in nasal tissues of patients with chronic rhinosinusitis and asthma. Medicine (Baltimore). 2016 Nov; 95(47):e5432. (SCI) Chien-Chia Huang; Chun-Hua Wang; Chia-Hsiang Fu; Chi-Che Huang; Po-Hung Chang; Yi-Wei Chen; Chia-Chen Wu; Pei-Wen Wu; Ta-Jen Lee*.
The link between chronic rhinosinusitis and asthma: A questionnaire-based study. Medicine (Baltimore). 2016 Aug; 95(31):e4294. (SCI) Chien-Chia Huang; Chun-Hua Wang; Chia-Hsiang Fu; Chi-Che Huang; Po-Hung Chang; I-Wei Chen; Ta-Jen Lee*.
Evaluation of depression and anxiety in empty nose syndrome after surgical treatment. Laryngoscope. 2016 Jun; 126(6):1284-9. Lee TJ, Fu CH, Wu CL, Tam YY, Huang CC, Chang PH, Chen YW, Wu MH.
Nasal nitric oxide in relation to quality-of-life improvements after endoscopic sinus surgery. Am J Rhinol Allergy. 2015 Nov-Dec;29(6):e187-91. Fu CH, Huang CC, Chen YW, Chang PH, Lee TJ.
Comparison of Short- and Long-term Hearing Outcomes of Successful Inlay Cartilage Tympanoplasty Between Small and Large Eardrum Perforations. Clin Exp Otorhinolaryngol. 2015 Dec;8(4):359-63. Wu PW, Wang WH, Huang CC, Lee TJ, Huang CC.
Extranodal Natural killer/T-cell lymphoma nasal type: Detection by computed tomography features. Laryngoscope. 2014 Dec;124(12):2670-5. Hsu YP, Chang PH, Lee TJ, Hung LY, Huang CC.
Seromucinous hamartoma in the nasal cavity medial to the middle turbinate: Report of 2 cases and review of the literature. Head Neck. 2014 May 11. doi: 10.1002/hed.23748. [Epub ahead of print] Huang CC, Lee TJ, Huang CC, Wu PW.
Intermittent hemoptysis and blood-tinged sputum. Castleman disease (CD), hyaline-vascular type JAMA Otolaryngol Head Neck Surg. 2013 Jul;139(7):743-4 Wu PW, Lee TJ, Huang CC, Lee KF, Huang CC.
The characteristics and new treatment paradigm of dental implant-related chronic rhinosinusitis. Am J Rhinol Allergy. 2013 May;27(3):237-44. Chen YW, Huang CC*, Chang PH, Chen CW, Wu CC, Fu CH, Lee TJ*.
Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Transnasal Endoscopic Marsupialization for a Huge Nasopalatine Duct Cyst With Nasal Involvement. J Oral Maxillofac Surg. 2013 May;71(5):891-3. Pei-Wen Wu; Ta-Jen Lee; Chi-Che Huang; Chien-Chia Huang*.
Extranodal natural killer/T-cell lymphoma, nasal type: clinical and computed tomography findings in the head and neck region. Laryngoscope. 2012 Dec;122(12):2632-9. Liang-Yueh Hung; Po-Hung Chang; Ta-Jen Lee; Yin-Ping Hsu; Yi-Wei Chen; Chia-Hsiang Fu; Chi-Che Huang*.
Downregulation of DLEC1 in sinonasal inverted papilloma and squamous cell carcinoma. J Otolaryngol Head Neck Surg. 2012 Apr;41(2):94-101. Po-Hung Chang; Chi-Che Huang; Ta-Jen Lee; Yun-Shien Lee; Chi-Neu Tsai*.
Role of flexible transnasal esophagoscopy and patient education in the management of globus pharyngeus. J Formos Med Assoc. 2012 Mar; 111(3):171-5. Chia-Chi Cheng; Tuan-Jen Fanga ;Ta-Jen Lee; Li-Ang Lee; Tsung-Ming Chen; Chin-Kuo Chen; Albert Re-Ming Yeh; Hao-Chun Huang; Han-Ren Hsiao; Wanni Lin; Ying-Ling Kuo; Hseuh-Yu Li*.
Similar cellular proliferation activities in nasal polyps and adjacent inferior turbinate. Am J Otolaryngol. 2012 Jan-Feb;33(1):14-9. Chia-Chen Wu ; Ta-Jen Lee ; Po-Hung Chang ; Chi-Neu Tsai ; Yun-Shien Lee ; Chia-Hsiang Fu ; Chi-Che Huang*.
Is otitis media with effusion almost always accompanying cleft palate in children?: the experience of 319 Asian patients. Laryngoscope. 2012 Jan;122(1):220-4. Yi-Wei Chen; Kuo-Ting Philip Chen; Po-Hung Chang; Jen-Liang Su; Chi-Che Huang; Ta-Jen Lee*.
Acute rhinosinusitis-related orbital infection in pediatric patients: a retrospective analysis. Ann Otol Rhinol Laryngol. 2011 Mar;120(3):185-90. Huang Shiang-Fu ; Ta-Jen Lee ; Lee Yun-Shien ; Chen Chien-Cheng ; Chin Shy-Chi ; Wang Ning-Chia.
Risk factors for protracted sinusitis in pediatrics after endoscopic sinus surgery. Auris Nasus Larynx. 2009 Dec;36(6):655-60. Ta-Jen Lee ; Chih-Wei Liang ; Po-Hung Chang ; Chi-Che Huang *.
Extensive paranasal sinus mucoceles: a 15-year review of 82 cases. Am J Otolaryngol. 2009 Jul-Aug;30(4):234-8. Ta-Jen Lee; Shang-Pei Li; Chia-Hsiang Fu; Chi-Che Huang; Po-Hung Chang; Yi-Wei Chen; Chiang-Wen Chen.