單定一醫師詳細介紹

國立台灣大學醫學院醫學士美國德州大學神經科學博士

臺北榮民總醫院神經醫學中心一般神經內科主治醫師臺北榮民總醫院神經醫學中心 科主任國立陽明大學神經學科教授

於109年6月4日起開診獲獎:1. 國科會87年度甲種研究獎勵2. 中華民國行政院退除役官兵輔導委員會102年優良醫師學術研究 :1.   Shan DE*, Soong BW, Yeh SI, Cheng CH, Wu ZA. Genetic screening for Huntington‘s disease in Chinese patients with involuntary movements. Clin Neurol Neurosurg 1997;99:244-247.2.   Shan DE*, Ho DMT, Chang C, Pan HC, Teng MMH. Hemichorea-hemiballism: An explanation for MR signal changes. AJNR Amer J Neuroradiol 1998;19:863-870.3.   Shan DE*. Delayed ischemic hyperintensity of T1-weighted MRI. Stroke 2000;31:797.4.   Shan DE*, Lee SJ, Chao LY, Yeh SI. Gait analysis in advanced Parkinsons disease - effect of levodopa and tolcapone. Canad J Neurol Sci 2001;28:70-75.5.  Shan DE*, Soong BW, Sun CM, Lee SJ, Liao KK, Liu RS. Spinocerebellar ataxia type 2 presenting as familial levodopa-responsive parkinsonism. Ann Neurol 2001;50:812-815.6.   Shan DE, Liu RS, Sun CM, Lee SJ, Liao KK, Soong BW. Presence of spinocerebellar ataxia type 2 gene mutation in a patient with apparently sporadic Parkinson’s disease – Clinical implications. Movement Disord 2004;19:1357-1360.7.   Shan DE*. Hemichorea-hemiballism associated with hyperintense putamen on T1-weighted MR images: an update and a hypothesis. Acta Neurol Taiwan 2004;13:170-177.8.   Shan DE*, Ho DMT, Pan HC, Chang C, Teng MMH. Presence of activated microglia in a high signal lesion on T1-weighted MR images: a biopsy sample reexamined. AJNR Amer J Neuroradiol 2007;28:602.9.    Wang V, Chuang TC, Soong BW, Shan DE*, Kao MC. Octarepeat changes of prion protein in Parkinsons disease. Parkinsonism Relat Disord 2009;1:53-58.10.  Liu KD, Shan DE, Kuo TB, Yang CC. The effects of bilateral stimulation of the subthalamic nucleus on heart rate variability in patients with Parkinsons disease. J Neurol 2013;260:1714-1723.

獲獎:1. 國科會87年度甲種研究獎勵2. 中華民國行政院退除役官兵輔導委員會102年優良醫師

學術研究 :

1.   Shan DE*, Soong BW, Yeh SI, Cheng CH, Wu ZA. Genetic screening for Huntington‘s disease in Chinese patients with involuntary movements. Clin Neurol Neurosurg 1997;99:244-247.

2.   Shan DE*, Ho DMT, Chang C, Pan HC, Teng MMH. Hemichorea-hemiballism: An explanation for MR signal changes. AJNR Amer J Neuroradiol 1998;19:863-870.

3.   Shan DE*. Delayed ischemic hyperintensity of T1-weighted MRI. Stroke 2000;31:797.

4.   Shan DE*, Lee SJ, Chao LY, Yeh SI. Gait analysis in advanced Parkinsons disease - effect of levodopa and tolcapone. Canad J Neurol Sci 2001;28:70-75.

5.  Shan DE*, Soong BW, Sun CM, Lee SJ, Liao KK, Liu RS. Spinocerebellar ataxia type 2 presenting as familial levodopa-responsive parkinsonism. Ann Neurol 2001;50:812-815.

6.   Shan DE, Liu RS, Sun CM, Lee SJ, Liao KK, Soong BW. Presence of spinocerebellar ataxia type 2 gene mutation in a patient with apparently sporadic Parkinson’s disease – Clinical implications. Movement Disord 2004;19:1357-1360.

7.   Shan DE*. Hemichorea-hemiballism associated with hyperintense putamen on T1-weighted MR images: an update and a hypothesis. Acta Neurol Taiwan 2004;13:170-177.

8.   Shan DE*, Ho DMT, Pan HC, Chang C, Teng MMH. Presence of activated microglia in a high signal lesion on T1-weighted MR images: a biopsy sample reexamined. AJNR Amer J Neuroradiol 2007;28:602.

9.    Wang V, Chuang TC, Soong BW, Shan DE*, Kao MC. Octarepeat changes of prion protein in Parkinsons disease. Parkinsonism Relat Disord 2009;1:53-58.

10.  Liu KD, Shan DE, Kuo TB, Yang CC. The effects of bilateral stimulation of the subthalamic nucleus on heart rate variability in patients with Parkinsons disease. J Neurol 2013;260:1714-1723.