黃尚本醫師詳細介紹

神經影像諮詢特別門診、神經藥物整合特別門診、神經疾病基因檢測

臺北醫學大學臨床醫學研究所醫學博士

台北醫學大學醫學系

https://orcid.org/0000-0002-3064-0899

萬芳醫院神經內科主治醫師

台安醫院腦神經內科主任

利用基因大數據資料庫，發現新的生物標記來預測癌症病患的預後與治療反應，並探索可能的分子機轉 (Identification of novel biomarkers for prognosis and therapeutic response in cancer patients and exploring the underlying molecular mechanisms)

將大數據資料視覺化與圖像化以利更深入的分析(visualization of big data for further analysis)

癌細胞抗藥機制的研究(identifying the mechanism of drug resistance in cancer cells)

臨床神經醫學：腦中風(stroke)

Li Wei, Yu-Kai Su, Chien-Min Lin, Tsu-Yi Chao, Shang-Pen Huang, Thanh-Tuan Huynh, Hsun-Jin Jan, Jacqueline Whang-Peng, Jeng-Fong Chiou, Alexander T.H. Wu, Michael HsiaoPreclinical investigation of ibrutinib, a Bruton’s kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes Oncotarget. 2016; 7:69961-69975. https://doi.org/10.18632/oncotarget.11572 (IF: not available, Oncology).

Shang-Pen Huang, Pei-Yao Liu, Chih-Jung Kuo, Chi-Long Chen, Wei-Jiunn Lee, Yu-Hui Tsai, Yuan-Feng LinThe Gαh-PLCδ1 signaling axis drives metastatic progression in triple-negative breast cancerJournal of Hematology & Oncology. 2017; 10:114 (IF: 23.168, Hematology: 4/78).

Shang-Pen Huang, Yu-Chan Chang, Qie Hua Low, Alexander T.H. Wu, Chi-Long Chen, Yuan-Feng Lin, Michael HsiaoBICD1 expression, as a Potential Biomarker for Predicting the Prognosis and Response to Therapy in Glioblastoma patientsOncotarget. 2017; 8(69):113766-113791. doi: 10.18632/oncotarget.22667 (IF: not available, Oncology).

Shang-Pen Huang, Jean Chiou, Yi-Hua Jan, Tsung-Ching Lai, Yung-Luen Yu, Michael Hsiao, Yuan-Feng LinOver-expression of Lysyl Oxidase is associated with poor prognosis and response to therapy of patients with lower grade gliomasBiochemical and Biophysical Research Communication. 2018; 501(3):619-627. (IF: 3.322, Biophysics: 39/72)

Yu-Chan Chang, Hsing-Fang Tsai, Shang-Pen Huang, Chi-Long Chen, Michael Hsiao, Wen-Chiuan TsaiEnrichment of Aldolase C Correlates with Low Non-Mutated IDH1 Expression and Predicts a Favorable Prognosis in Glioblastomas.Cancers (Basel). 2019 Aug 23;11(9). (IF: 6.575, Oncology: 60/245).

Shang-Pen Huang, Yung-Chieh Chan, Shang-Yu Huang, Yuan-Feng LinOverexpression of PSAT1 Gene is a Favorable Prognostic Marker in Lower-Grade Gliomas and Predicts a Favorable Outcome in Patients with IDH1 Mutations and Chromosome 1p19q CodeletionCancers (Basel). 2019 Dec 18;12(1). (IF: 6.575, Oncology: 60/245).