專業權威 · 完整履歷 · 即時門診
國泰醫療財團法人國泰綜合醫院
主治醫師
主任級醫師
| 星期一 | 24 小時營業 |
| 星期二 | 24 小時營業 |
| 星期三 | 24 小時營業 |
| 星期四 | 24 小時營業 |
| 星期五 | 24 小時營業 |
| 星期六 | 24 小時營業 |
| 星期日 | 24 小時營業 |
陽明醫學院醫學系
台灣大學管理學院EMBA高階公共管理組碩士
台灣大學公共衛生學院職業醫學與工業衛生研究所博士
台南一中
輔仁大學醫學系副教授
輔仁大學醫學系助理教授
台灣精神流行病學學會秘書長
台灣精神醫學會專科醫師
華梵大學兼任講師、心理醫師
台北市立聯合醫院松德院區(原台北市立療養院)精神科訓練
國泰綜合醫院精神科主任
國泰綜合醫院精神科主治醫師
Omega-3 Fatty Acids and Mood disorder
Wu SK, Yang KJ, Liu WC, Malau IA, Zailani H, Chang CH, Huang SY, Chang JP, Chiu WC, Su KP. The Efficacy of Omega-3 Fatty Acids as the Monotherapy for Depression: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. Nutrients. 2024 Oct 29;16(21):3688. doi: 10.3390/nu16213688. (Corresponding authorship)
Zailani H, Wu SK, Yang KJ, Malau IA, Liao HF, Chung YL, Chang JP, Chiu WC, Su KP. Omega-3 polyunsaturated fatty acids in the prevention of relapse in patients with stable bipolar disorder: A 6-month pilot randomized controlled trial. Psychiatry Res. 2024 Jan;331:115633. doi: 10.1016/j.psychres.2023.115633. (Corresponding authorship)
Malau IA, Chang JP, Lin YW, Chang CC, Chiu WC, Su KP. Omega-3 Fatty Acids and Neuroinflammation in Depression: Targeting Damage-Associated Molecular Patterns and Neural Biomarkers. Cells. 2024 Oct 29;13(21):1791.
Zailani H, Wang WL, Satyanarayanan SK, Chiu WC, Liu WC, Sung YS, Chang JP, Su KP. Omega-3 Polyunsaturated Fatty Acids and Blood-Brain Barrier Integrity in Major Depressive Disorder: Restoring Balance for Neuroinflammation and Neuroprotection. Yale J Biol Med. 2024 Sep 30;97(3):349-363. doi: 10.59249/YZLQ4631. eCollection 2024 Sep.
Zailani H, Chang JP, Chiu WC, Chang CJ, Su KP. Addressing methodological concerns in omega-3 trial for bipolar disorder relapse prevention. Psychiatry Res. 2024 Jul;337:115947. doi: 10.1016/j.psychres.2024.115947. Epub 2024 May 3.
Iqbal AZ, Wu SK, Zailani H, Chiu WC, Liu WC, Su KP, Lee SD. Effects of Omega-3 Polyunsaturated Fatty Acids Intake on Vasomotor Symptoms, Sleep Quality and Depression in Postmenopausal Women: A Systematic Review. Nutrients. 2023 Sep 30;15(19):4231. doi: 10.3390/nu15194231.
Mood disorder and Antidepressants
Lesmana MHS, Le NQK, Chiu WC, Chung KH, Wang CY, Irham LM, Chung MH. Genomic-Analysis-Oriented Drug Repurposing in the Search for Novel Antidepressants. Biomedicines. 2022 Aug 11;10(8):1947. doi: 10.3390/biomedicines10081947.
Thi Ngoc Pham A, Chang HC, Malau IA, Chiu WC, Huang KC, Chang JP, Tang CH, Su KP. Change of employment status in patients with depression - A longitudinal study using national claims data. Asian J Psychiatr. 2023 Apr 18;84:103595. doi: 10.1016/j.ajp.2023.103595.
Chen AC, Huang KL, Chen HM, Chen PC, Chen VC, Chiu WC. Antidepressants and the risk of myocardial infarction among patients with diabetes: A population-based cohort study. J Affect Disord. 2021 Jul 8;294:109-114. doi: 10.1016/j.jad.2021.06.078. Online ahead of print. (Corresponding authorship)(IF=4.839)
Wu LS, Huang MC, Fann CS, Lane HY, Kuo CJ, Chiu WC, Kwok PY, Cheng AT. Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population. Transl Psychiatry. 2021 May 20;11(1):301. doi: 10.1038/s41398-021-01407-6.PMID: 34016946
Addiction and Alcohol
Chiu WC, Shan JC, Yang YH, Chen VCH, Chen PC. Statins and the risks of decompensated liver cirrhosis and hepatocellular carcinoma determined in patients with alcohol use disorder. Drug and Alcohol Dependence, 2021: 228, 109096. (IF=4.852)
Chen VC, Lee MJ, Yang YH, Lu ML, Chiu WC, Dewey ME. Selective serotonin reuptake inhibitors use and hepatocellular carcinoma in patients with alcohol use disorder. Drug Alcohol Depend. 2021 Feb 1;219:108495. doi: 10.1016/j.drugalcdep.2020.108495. Epub 2020 Dec 31. (Corresponding authorship) (IF=4.852)
Wang YC, Chiu WC, Cheng CN, Lee C, Huang ACW. Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine. Neurosci Lett. 2021 Jun 18;760:136076. doi: 10.1016/j.neulet.2021.136076. Online ahead of print. PMID: 34153368
Interferon-α and Depressive disorder
Sun CF, Chiu WC, Chen PC, Chang HC, Guu TW, Shityakov S, Miller AH, Felger JC, Chang JP, Su KP. Depression-free after Interferon-α exposure indicates less incidence of depressive disorder: A longitudinal study in Taiwan. Brain Behav Immun. 2020 Aug;88:125-131. doi: 10.1016/j.bbi.2020.05.044. Epub 2020 May 17. PMID: 32434045 (Corresponding authorship) (IF=19.227)
Chiu WC, Lu ML, Chang CC. Mental Disorders and Interferon Nontreatment in Hepatitis C Virus Infection-a Population Based Cohort Study. Psychiatry Investig. 2020 Mar;17(3):268-274. doi: 10.30773/pi.2019.0254. Epub 2020 Mar 11.
Sun CF, Chiu WC, Su KP. Reply to "Does the decreased incidence of new-onset depression in patients with interferon-α therapy indicate the protective effect of interferon-α against depression?". Brain Behav Immun. 2021 Feb 24:S0889-1591(21)00082-9. doi: 10.1016/j.bbi.2021.02.017. (IF=19.227)
Sun CF, Chiu WC, Su KP. Somatic Symptoms in Inflammation-related Depression: Reply to" Letter for Depression-free after Interferon-α exposure indicates less incidence of depressive disorder: A longitudinal study in Taiwan". Brain, behavior, and immunity, 2022: 101, S0889-1591. (IF=19.227)
Dementia and Cognitive function
Cheng YC, Liu SI, Chen CH, Liu HC, Lu ML, Chang CJ, Chiu WC, Sun IW, Yao LS, Chiu CC, Robert S. Comparison of cognitive function between early- and late-onset late-life depression in remission. Psychiatry Res. 2020 May 21;290:113051. doi: 10.1016/j.psychres.2020.113051.
Mood disorder and Antidepressants
Thi Ngoc Pham A, Chang HC, Malau IA, Chiu WC, Huang KC, Chang JP, Tang CH, Su KP. Change of employment status in patients with depression - A longitudinal study using national claims data. Asian J Psychiatr. 2023 Apr 18;84:103595. doi: 10.1016/j.ajp.2023.103595.
Chen AC, Huang KL, Chen HM, Chen PC, Chen VC, Chiu WC. Antidepressants and the risk of myocardial infarction among patients with diabetes: A population-based cohort study. J Affect Disord. 2021 Jul 8;294:109-114. doi: 10.1016/j.jad.2021.06.078. Online ahead of print. (Corresponding authorship)(IF=4.839)
Wu LS, Huang MC, Fann CS, Lane HY, Kuo CJ, Chiu WC, Kwok PY, Cheng AT. Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population. Transl Psychiatry. 2021 May 20;11(1):301. doi: 10.1038/s41398-021-01407-6.PMID: 34016946
Mental disorder and Schizophrenia
Chen DTL, Chang JPC, Cheng SW, Chang HC, Hsu JH, Chang HH, Chiu WC, Su KP. (2021). Kawasaki Disease in Childhood and Psychiatric Disorders: A Population-Based Case-Control Prospective Study in Taiwan. Brain, behavior, and immunity, 2022: 100, 105-111. (Corresponding authorship) (IF=19.227)
Chen DTL, Chang HC, Chiu WC, Su KP. Back to the Future-On Prospective Design in Retrospective Nested Case-Control Study: Reply to the Letter to the Editor "Queries Regarding Retrospective Study Design and the Recruitment of People with Psychiatric Disorders". Brain Behav Immun. 2022 May 13:S0889-1591(22)00127-1. (IF=19.227). (Corresponding authorship)
Cancer
Chen CJ, Chiu WC, Tseng YH, Lin CM, Yang HY, Yang YH, Chen PC. Aristolochic acid and the risk of cancers in patients with type 2 diabetes: Nationwide population-based cohort study. Phytomedicine. 2022 Mar 3;99:154023. doi: 10.1016/j.phymed.2022.154023. (IF=6.656)
Chen VC, Hsieh YH, Lin TC, Lu ML, Liao YT, Yang YH, Hsu TC, Stewart R, Weng JC, Lee MJ, Chiu WC, Tzang BS. New Use for Old Drugs: The Protective Effect of Risperidone on Colorectal Cancer. Cancers (Basel). 2020 Jun 12;12(6):E1560. doi: 10.3390/cancers12061560. (Corresponding authorship)
Others
1. Varicose veins are associated with an increased risk of mitral valve Lee ML, Chou WY, Kao YW, Chen MC, Shia BC, Lee PS, Chen TH, Lin TY, Huang SY, Su YB, Chiu WC. regurgitation: a nationwide population-based cohort study. Int Angiol. 2023 Jun 22. doi: 10.23736/S0392-9590.23.05053-8. Online ahead of print.
Wu SK, Yang KJ, Liu WC, Malau IA, Zailani H, Chang CH, Huang SY, Chang JP, Chiu WC, Su KP. The Efficacy of Omega-3 Fatty Acids as the Monotherapy for Depression: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. Nutrients. 2024 Oct 29;16(21):3688. doi: 10.3390/nu16213688. (Corresponding authorship)
Zailani H, Wu SK, Yang KJ, Malau IA, Liao HF, Chung YL, Chang JP, Chiu WC, Su KP. Omega-3 polyunsaturated fatty acids in the prevention of relapse in patients with stable bipolar disorder: A 6-month pilot randomized controlled trial. Psychiatry Res. 2024 Jan;331:115633. doi: 10.1016/j.psychres.2023.115633. (Corresponding authorship)
Malau IA, Chang JP, Lin YW, Chang CC, Chiu WC, Su KP. Omega-3 Fatty Acids and Neuroinflammation in Depression: Targeting Damage-Associated Molecular Patterns and Neural Biomarkers. Cells. 2024 Oct 29;13(21):1791.
Zailani H, Wang WL, Satyanarayanan SK, Chiu WC, Liu WC, Sung YS, Chang JP, Su KP. Omega-3 Polyunsaturated Fatty Acids and Blood-Brain Barrier Integrity in Major Depressive Disorder: Restoring Balance for Neuroinflammation and Neuroprotection. Yale J Biol Med. 2024 Sep 30;97(3):349-363. doi: 10.59249/YZLQ4631. eCollection 2024 Sep.
Zailani H, Chang JP, Chiu WC, Chang CJ, Su KP. Addressing methodological concerns in omega-3 trial for bipolar disorder relapse prevention. Psychiatry Res. 2024 Jul;337:115947. doi: 10.1016/j.psychres.2024.115947. Epub 2024 May 3.
Iqbal AZ, Wu SK, Zailani H, Chiu WC, Liu WC, Su KP, Lee SD. Effects of Omega-3 Polyunsaturated Fatty Acids Intake on Vasomotor Symptoms, Sleep Quality and Depression in Postmenopausal Women: A Systematic Review. Nutrients. 2023 Sep 30;15(19):4231. doi: 10.3390/nu15194231.
Lesmana MHS, Le NQK, Chiu WC, Chung KH, Wang CY, Irham LM, Chung MH. Genomic-Analysis-Oriented Drug Repurposing in the Search for Novel Antidepressants. Biomedicines. 2022 Aug 11;10(8):1947. doi: 10.3390/biomedicines10081947.
Thi Ngoc Pham A, Chang HC, Malau IA, Chiu WC, Huang KC, Chang JP, Tang CH, Su KP. Change of employment status in patients with depression - A longitudinal study using national claims data. Asian J Psychiatr. 2023 Apr 18;84:103595. doi: 10.1016/j.ajp.2023.103595.
Chen AC, Huang KL, Chen HM, Chen PC, Chen VC, Chiu WC. Antidepressants and the risk of myocardial infarction among patients with diabetes: A population-based cohort study. J Affect Disord. 2021 Jul 8;294:109-114. doi: 10.1016/j.jad.2021.06.078. Online ahead of print. (Corresponding authorship)(IF=4.839)
Wu LS, Huang MC, Fann CS, Lane HY, Kuo CJ, Chiu WC, Kwok PY, Cheng AT. Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population. Transl Psychiatry. 2021 May 20;11(1):301. doi: 10.1038/s41398-021-01407-6.PMID: 34016946
Chiu WC, Shan JC, Yang YH, Chen VCH, Chen PC. Statins and the risks of decompensated liver cirrhosis and hepatocellular carcinoma determined in patients with alcohol use disorder. Drug and Alcohol Dependence, 2021: 228, 109096. (IF=4.852)
Chen VC, Lee MJ, Yang YH, Lu ML, Chiu WC, Dewey ME. Selective serotonin reuptake inhibitors use and hepatocellular carcinoma in patients with alcohol use disorder. Drug Alcohol Depend. 2021 Feb 1;219:108495. doi: 10.1016/j.drugalcdep.2020.108495. Epub 2020 Dec 31. (Corresponding authorship) (IF=4.852)
Wang YC, Chiu WC, Cheng CN, Lee C, Huang ACW. Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine. Neurosci Lett. 2021 Jun 18;760:136076. doi: 10.1016/j.neulet.2021.136076. Online ahead of print. PMID: 34153368
Sun CF, Chiu WC, Chen PC, Chang HC, Guu TW, Shityakov S, Miller AH, Felger JC, Chang JP, Su KP. Depression-free after Interferon-α exposure indicates less incidence of depressive disorder: A longitudinal study in Taiwan. Brain Behav Immun. 2020 Aug;88:125-131. doi: 10.1016/j.bbi.2020.05.044. Epub 2020 May 17. PMID: 32434045 (Corresponding authorship) (IF=19.227)
Chiu WC, Lu ML, Chang CC. Mental Disorders and Interferon Nontreatment in Hepatitis C Virus Infection-a Population Based Cohort Study. Psychiatry Investig. 2020 Mar;17(3):268-274. doi: 10.30773/pi.2019.0254. Epub 2020 Mar 11.
Sun CF, Chiu WC, Su KP. Reply to "Does the decreased incidence of new-onset depression in patients with interferon-α therapy indicate the protective effect of interferon-α against depression?". Brain Behav Immun. 2021 Feb 24:S0889-1591(21)00082-9. doi: 10.1016/j.bbi.2021.02.017. (IF=19.227)
Sun CF, Chiu WC, Su KP. Somatic Symptoms in Inflammation-related Depression: Reply to" Letter for Depression-free after Interferon-α exposure indicates less incidence of depressive disorder: A longitudinal study in Taiwan". Brain, behavior, and immunity, 2022: 101, S0889-1591. (IF=19.227)
Cheng YC, Liu SI, Chen CH, Liu HC, Lu ML, Chang CJ, Chiu WC, Sun IW, Yao LS, Chiu CC, Robert S. Comparison of cognitive function between early- and late-onset late-life depression in remission. Psychiatry Res. 2020 May 21;290:113051. doi: 10.1016/j.psychres.2020.113051.
Thi Ngoc Pham A, Chang HC, Malau IA, Chiu WC, Huang KC, Chang JP, Tang CH, Su KP. Change of employment status in patients with depression - A longitudinal study using national claims data. Asian J Psychiatr. 2023 Apr 18;84:103595. doi: 10.1016/j.ajp.2023.103595.
Chen AC, Huang KL, Chen HM, Chen PC, Chen VC, Chiu WC. Antidepressants and the risk of myocardial infarction among patients with diabetes: A population-based cohort study. J Affect Disord. 2021 Jul 8;294:109-114. doi: 10.1016/j.jad.2021.06.078. Online ahead of print. (Corresponding authorship)(IF=4.839)
Wu LS, Huang MC, Fann CS, Lane HY, Kuo CJ, Chiu WC, Kwok PY, Cheng AT. Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population. Transl Psychiatry. 2021 May 20;11(1):301. doi: 10.1038/s41398-021-01407-6.PMID: 34016946
Chen DTL, Chang JPC, Cheng SW, Chang HC, Hsu JH, Chang HH, Chiu WC, Su KP. (2021). Kawasaki Disease in Childhood and Psychiatric Disorders: A Population-Based Case-Control Prospective Study in Taiwan. Brain, behavior, and immunity, 2022: 100, 105-111. (Corresponding authorship) (IF=19.227)
Chen DTL, Chang HC, Chiu WC, Su KP. Back to the Future-On Prospective Design in Retrospective Nested Case-Control Study: Reply to the Letter to the Editor "Queries Regarding Retrospective Study Design and the Recruitment of People with Psychiatric Disorders". Brain Behav Immun. 2022 May 13:S0889-1591(22)00127-1. (IF=19.227). (Corresponding authorship)
Chen CJ, Chiu WC, Tseng YH, Lin CM, Yang HY, Yang YH, Chen PC. Aristolochic acid and the risk of cancers in patients with type 2 diabetes: Nationwide population-based cohort study. Phytomedicine. 2022 Mar 3;99:154023. doi: 10.1016/j.phymed.2022.154023. (IF=6.656)
Chen VC, Hsieh YH, Lin TC, Lu ML, Liao YT, Yang YH, Hsu TC, Stewart R, Weng JC, Lee MJ, Chiu WC, Tzang BS. New Use for Old Drugs: The Protective Effect of Risperidone on Colorectal Cancer. Cancers (Basel). 2020 Jun 12;12(6):E1560. doi: 10.3390/cancers12061560. (Corresponding authorship)
1. Varicose veins are associated with an increased risk of mitral valve Lee ML, Chou WY, Kao YW, Chen MC, Shia BC, Lee PS, Chen TH, Lin TY, Huang SY, Su YB, Chiu WC. regurgitation: a nationwide population-based cohort study. Int Angiol. 2023 Jun 22. doi: 10.23736/S0392-9590.23.05053-8. Online ahead of print.
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